ARA-290

How does ARA-290 work?

ARA-290 exerts its effects by selectively activating the innate repair receptor (IRR), a heteromeric complex composed of EPO receptor (EPOR) and β common receptor (βcR) subunits. This specific interaction triggers a cascade of signaling events that lead to anti-inflammatory, tissue-protective, and repair-promoting effects. ARA-290 has been shown to modulate the immune response by reducing the production of pro-inflammatory cytokines and increasing the expression of anti-inflammatory mediators. Additionally, it promotes the survival and function of various cell types, including endothelial cells, cardiomyocytes, and neurons, under stress conditions.

Handling & Safety

Handle as a laboratory research chemical of unknown hazard. Use gloves and eye protection, avoid inhalation of the lyophilized powder, and follow standard laboratory handling procedures. Reconstitute and store according to the product label. Lyophilized material should be kept cool, dry and protected from light; reconstituted material should be held at 2-8°C and protected from light. The safety profile of ARA-290 has not been established. This compound is supplied for laboratory research use only and is not approved for human or veterinary use.

Summary

ARA 290 peptide is a promising synthetic peptide that mimics the tissue-protective and repair-promoting properties of EPO without stimulating erythropoiesis. By selectively activating the innate repair receptor, ARA-290 exerts potent anti-inflammatory, neuroprotective, cardioprotective, and renoprotective effects in various preclinical models. Clinical studies have also demonstrated its potential in tissue-protective effects and wound research. With its favorable safety profile and wide-ranging research relevance, ARA-290 represents an exciting avenue for the development of novel treatments for a variety of conditions characterized by tissue damage and inflammation. For laboratories searching for ara 290 for sale or looking to buy ara 290, sourcing from a reputable research-grade supplier with verified purity and analytical validation is essential to ensure experimental accuracy. Research context only. No human or veterinary use.

Certificate of Analysis (COA)

Resource

All products on this site are for research and development use only. Products are not for human consumption of any kind. Neither the statements nor the products offered are intended to diagnose, treat, cure, or prevent any disease.