Oxytocin

How does Oxytocin work?

Oxytocin exerts its effects by binding to specific G protein-coupled receptors, known as oxytocin receptors (OXTRs), which are expressed in various tissues throughout the body, including the brain, uterus, and mammary glands. Upon binding to OXTRs, oxytocin triggers intracellular signaling cascades that lead to diverse physiological responses, such as uterine contractions during labor, milk ejection during lactation, and the promotion of social bonding and trust.In the central nervous system, oxytocin acts as a neuromodulator, influencing the activity of various neurotransmitter systems, such as dopamine, serotonin, and GABA. These interactions are thought to underlie oxytocin's effects on social behavior, stress regulation, and emotional processing. Oxytocin peptide has been shown to enhance the salience of social stimuli, facilitate social recognition and memory, and reduce anxiety and stress responses in mammal models.

Handling & Safety

Handle as a laboratory research chemical of unknown hazard. Use gloves and eye protection, avoid inhalation of the lyophilized powder, and follow standard laboratory handling procedures. Reconstitute and store according to the product label. Lyophilized material should be kept cool, dry and protected from light; reconstituted material should be held at 2-8°C and protected from light. The safety profile of Oxytocin has not been established. This compound is supplied for laboratory research use only and is not approved for human or veterinary use.

Summary

Oxytocin is a neuropeptide hormone with a wide range of physiological functions, including its well-known roles in social bonding, sexual reproduction, and stress regulation. The potential research applications of oxytocin in neuropsychiatric and neurodevelopmental disorders, such as autism spectrum disorder, social anxiety disorder, schizophrenia, chronic pain conditions, and metabolic disorders, have garnered significant attention in recent years. While research has shown promising results, further large-scale clinical trials are needed to establish the long-term safety and efficacy of oxytocin administration for these indications. As a research peptide, oxytocin continues to be a valuable tool in elucidating the complex mechanisms underlying social behavior, emotional processing, stress regulation, and appetite control, paving the way for the development of novel research approaches for a range of neuropsychiatric and metabolic conditions. Research context only. No human or veterinary use.

Certificate of Analysis (COA)

Resource

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